Basic Information
ID: ALA4682703
Type: Binding
Description: Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylation at 1 nM preincubated for 30 mins followed by PACAP stimulation and measured after 30 mins by Western blot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Pituitary adenylate cyclase-activating polypeptide type I receptor(ALA5399)
Document: ALA4680128
Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylation at 1 nM preincubated for 30 mins followed by PACAP stimulation and measured after 30 mins by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4682703
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.82 | 1.65 | 1.65 |
| 338.37 | 1.00 | 1.00 |