Basic Information
ID: ALA4682923
Type: Binding
Description: Inhibition of AcrB in Escherichia coli BW25113 assessed as potentiation of levofloxacin induced antibacterial activity by measuring levofloxacin MIC at 128 ug/ml measured after 18 hrs by checkerboard titration method (Rvb = 0.06 ug/ml)
Organism: Escherichia coli BW25113
Activity Charts
Bioactivity
Activity Types for Assay ALA4682923
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 3.57 | 3.57 |
| 276.76 | 4.32 | 4.32 |
| 274.32 | 3.07 | 3.07 |
| 325.29 | 3.09 | 3.09 |
| 289.29 | 1.48 | 1.48 |
| 271.32 | 2.38 | 2.38 |
| 305.29 | 1.19 | 1.19 |
| 273.29 | 1.78 | 1.78 |
| 336.19 | 2.83 | 2.83 |
| 258.32 | 3.37 | 3.37 |
| 290.31 | 2.78 | 2.78 |
| 366.46 | 6.56 | 6.56 |
| 287.32 | 1.23 | 1.23 |
| 321.21 | 4.43 | 4.43 |
| 272.30 | 1.65 | 1.65 |
| 260.29 | 2.68 | 2.68 |
| 316.40 | 4.24 | 4.24 |
| 302.37 | 3.85 | 3.85 |
| 288.34 | 3.46 | 3.46 |
| 272.30 | 1.65 | 1.65 |