Basic Information
ID: ALA4683559
Type: Binding
Description: Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in MLL1 binding to WDR5 WIN site by 5-FAM probe based fluorescence polarization assay
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4683559
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.37 | 3.52 | 3.52 |
| 315.40 | 2.89 | 2.89 |
| 299.40 | 3.88 | 3.88 |
| 359.45 | 2.99 | 2.99 |
| 345.42 | 2.90 | 2.90 |
| 345.42 | 2.90 | 2.90 |
| 369.37 | 3.52 | 3.52 |
| 270.36 | 3.18 | 3.18 |
| 425.46 | 3.59 | 3.59 |
| 332.45 | 3.62 | 3.62 |
| 427.43 | 2.95 | 2.95 |
| 271.35 | 2.57 | 2.57 |
| 316.38 | 3.16 | 3.16 |