Basic Information
ID: ALA4683921
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858/T790M mutant assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4683921
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 259.26 | 0.03 | 0.03 |
| 499.62 | 4.51 | 4.51 |
| 430.57 | 2.07 | 2.07 |
| 1155.42 | ||
| 1118.39 | ||
| 926.11 | 6.44 | 6.44 |
| 870.99 | 4.95 | 4.95 |
| 913.03 | 3.60 | 3.60 |
| 899.99 | 3.28 | 3.28 |
| 994.15 | 5.91 | 5.91 |
| 913.07 | 6.12 | 6.12 |
| 1070.35 | ||
| 1042.30 | ||
| 899.04 | 5.73 | 5.73 |
| 1074.34 | ||
| 885.02 | 5.34 | 5.34 |