Protac activity at E3 ubiquitin ligase/EGFR in human HCC827 cells assessed as increase in degradation of EGFR at 100 nM pretreated with VHL-L for 5 hr...

Basic Information

ID: ALA4683932

Type: Binding

Description: Protac activity at E3 ubiquitin ligase/EGFR in human HCC827 cells assessed as increase in degradation of EGFR at 100 nM pretreated with VHL-L for 5 hrs followed by compound addition and measured after 32 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HCC827

Target:  Unchecked(ALA612545)

Document:  ALA4680163

Protac activity at E3 ubiquitin ligase/EGFR in human HCC827 cells assessed as increase in degradation of EGFR at 100 nM pretreated with VHL-L for 5 hrs followed by compound addition and measured after 32 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1070.35