Basic Information
ID: ALA4683934
Type: Binding
Description: Protac activity at E3 ubiquitin ligase/EGFR in human HCC827 cells assessed as increase in degradation of EGFR at 1 to 10 uM pretreated with MLN-4924 for 6 hrs followed by compound addition and measured after 30 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: Unchecked(ALA612545)
Document: ALA4680163
Protac activity at E3 ubiquitin ligase/EGFR in human HCC827 cells assessed as increase in degradation of EGFR at 1 to 10 uM pretreated with MLN-4924 for 6 hrs followed by compound addition and measured after 30 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4683934
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 913.07 | 6.12 | 6.12 |
| 1070.35 |