ID: ALA4683935
Type: Binding
Description: Protac activity at E3 ubiquitin ligase/EGFR in human NCI-H1975 cells harboring EGFR T790M mutant assessed as increase in degradation of EGFR at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: Unchecked(ALA612545)
Document: ALA4680163
Protac activity at E3 ubiquitin ligase/EGFR in human NCI-H1975 cells harboring EGFR T790M mutant assessed as increase in degradation of EGFR at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis: 1
Bioactivity
Activity Types for Assay ALA4683935
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
913.07 | 6.12 | 6.12 |
1070.35 |