Protac activity at E3 ubiquitin ligase/EGFR in human NCI-H1975 cells harboring EGFR T790M mutant assessed as increase in degradation of EGFR at 0.1 to...

Basic Information

ID: ALA4683935

Type: Binding

Description: Protac activity at E3 ubiquitin ligase/EGFR in human NCI-H1975 cells harboring EGFR T790M mutant assessed as increase in degradation of EGFR at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H1975

Target:  Unchecked(ALA612545)

Document:  ALA4680163

Protac activity at E3 ubiquitin ligase/EGFR in human NCI-H1975 cells harboring EGFR T790M mutant assessed as increase in degradation of EGFR at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
913.076.126.12
1070.35