Basic Information
ID: ALA4684494
Type: Binding
Description: Inhibition of DOT1L in mouse bone marrow cell transformed with MLL-AF9 cells assessed as reduction in H3K36 methylation at 100 uM measured upto 9 days by Western blot analysis
Format: BAO_0000221
Organism: Mus musculus
Cell type: Bone marrow cell
Target: Histone H3 methyltransferase DOT1 variant d(ALA4739691)
Document: ALA4680176
Inhibition of DOT1L in mouse bone marrow cell transformed with MLL-AF9 cells assessed as reduction in H3K36 methylation at 100 uM measured upto 9 days by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4684494
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.52 | 0.23 | 0.23 |