Basic Information
ID: ALA4684501
Type: Binding
Description: Binding affinity to recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as increase in melting temperature incubated for 1 min by 1,8-ANS probe based thermal shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA4680176
Binding affinity to recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as increase in melting temperature incubated for 1 min by 1,8-ANS probe based thermal shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4684501
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.53 | 1.97 | 1.97 |