Basic Information
ID: ALA4684783
Type: Binding
Description: Inhibition of human recombinant HDAC1 at 10 uM preincubated for 10 mins followed by addition of substrate fluor De Lys SIRT1 deacetylase measured after 30 mins by fluorescent plate reader analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4684783
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 390.42 | 3.38 | 3.38 |
| 490.47 | 3.70 | 3.70 |
| 379.38 | 1.96 | 1.96 |
| 484.52 | 3.69 | 3.69 |
| 425.85 | 2.64 | 2.64 |
| 409.40 | 1.72 | 1.72 |
| 523.38 | 4.98 | 4.98 |
| 409.40 | 1.97 | 1.97 |
| 428.28 | 2.76 | 2.76 |
| 454.49 | 3.43 | 3.43 |
| 395.37 | 1.74 | 1.74 |
| 431.81 | 2.50 | 2.50 |
| 381.34 | 1.35 | 1.35 |
| 413.82 | 2.36 | 2.36 |
| 413.82 | 2.62 | 2.62 |
| 484.52 | 3.44 | 3.44 |
| 442.30 | 3.15 | 3.15 |
| 448.27 | 3.02 | 3.02 |
| 415.36 | 1.99 | 1.99 |
| 490.47 | 3.96 | 3.96 |
| 454.49 | 3.68 | 3.68 |
| 367.31 | 0.96 | 0.96 |
| 431.81 | 2.75 | 2.75 |
| 523.38 | 4.73 | 4.73 |
| 472.48 | 3.82 | 3.82 |
| 448.27 | 3.27 | 3.27 |
| 488.94 | 4.08 | 4.08 |
| 506.93 | 4.22 | 4.22 |
| 409.39 | 2.13 | 2.13 |
| 415.36 | 2.24 | 2.24 |
| 397.37 | 2.10 | 2.10 |
| 488.94 | 4.33 | 4.33 |
| 379.38 | 1.71 | 1.71 |
| 397.37 | 1.85 | 1.85 |
| 506.93 | 4.47 | 4.47 |
| 472.48 | 3.57 | 3.57 |