Basic Information
ID: ALA4685314
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of recombinant human GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression system to IC50 for inhibition of recombinant human GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4680201
Selectivity ratio of IC50 for inhibition of recombinant human GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression system to IC50 for inhibition of recombinant human GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4685314
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 414.47 | 3.58 | 3.58 |
| 414.47 | 3.58 | 3.58 |
| 363.38 | 1.93 | 1.93 |
| 414.47 | 3.58 | 3.58 |
| 364.41 | 2.59 | 2.59 |
| 334.38 | 3.14 | 3.14 |
| 377.41 | 2.58 | 2.58 |
| 377.41 | 2.58 | 2.58 |
| 401.47 | 3.85 | 3.85 |
| 415.50 | 4.24 | 4.24 |
| 401.47 | 3.85 | 3.85 |
| 415.50 | 4.24 | 4.24 |
| 391.48 | 3.16 | 3.16 |
| 377.45 | 2.77 | 2.77 |
| 333.36 | 2.47 | 2.47 |
| 364.41 | 2.85 | 2.85 |
| 377.41 | 2.58 | 2.58 |
| 364.41 | 2.85 | 2.85 |
| 421.46 | 1.97 | 1.97 |
| 401.47 | 3.85 | 3.85 |
| 435.49 | 2.36 | 2.36 |
| 401.47 | 3.85 | 3.85 |
| 390.41 | 1.59 | 1.59 |
| 378.44 | 3.24 | 3.24 |
| 378.44 | 3.24 | 3.24 |
| 377.41 | 1.95 | 1.95 |
| 414.47 | 3.58 | 3.58 |
| 415.50 | 4.24 | 4.24 |
| 471.52 | 2.69 | 2.69 |
| 364.41 | 2.85 | 2.85 |
| 378.44 | 3.24 | 3.24 |
| 320.36 | 2.75 | 2.75 |
| 364.41 | 2.85 | 2.85 |
| 472.55 | 3.35 | 3.35 |
| 458.52 | 2.96 | 2.96 |