Basic Information
ID: ALA4685319
Type: Binding
Description: Inhibition of JAK3 in anti-CD3/-CD28 coated mouse T cells assessed as reduction in IL2-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by IL2 stimulation and measured after 30 mins by Western blot analysis
Format: BAO_0000221
Organism: Mus musculus
Cell type: T cell
Target: Tyrosine-protein kinase JAK3(ALA5250)
Document: ALA4680201
Inhibition of JAK3 in anti-CD3/-CD28 coated mouse T cells assessed as reduction in IL2-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by IL2 stimulation and measured after 30 mins by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4685319
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.47 | 3.85 | 3.85 |
| 415.50 | 4.24 | 4.24 |
| 364.41 | 2.85 | 2.85 |