Basic Information
ID: ALA4685763
Type: Binding
Description: Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation by measuring remaining BCL-XL level at 100 nM measured after 16 hrs by immunoblotting analysis relative to control
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA4685763
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1556.42 | ||
| 1514.38 | ||
| 1579.40 | ||
| 1516.35 | ||
| 1542.39 | ||
| 1459.30 | ||
| 1560.36 | ||
| 1542.43 | ||
| 1528.36 | ||
| 1486.28 | ||
| 1487.31 | ||
| 1515.41 | ||
| 1500.31 | ||
| 1574.39 | ||
| 1473.33 | ||
| 1528.41 | ||
| 1514.34 | ||
| 1445.27 | ||
| 1544.36 | ||
| 1501.38 | ||
| 1535.35 | ||
| 1487.35 | ||
| 1500.35 | ||
| 1560.41 | ||
| 1491.30 |