Basic Information
ID: ALA4685765
Type: Binding
Description: Protac activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation by measuring remaining BCL-XL level at 50 nM measured after 16 hrs by immunoblotting analysis relative to control
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA4685765
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1329.00 | ||
| 1371.08 | ||
| 1314.97 | ||
| 1245.91 | ||
| 1405.10 | ||
| 1286.96 | ||
| 1361.04 | ||
| 1394.07 | ||
| 1231.88 | ||
| 1315.02 | ||
| 1404.07 | ||
| 1305.96 | ||
| 1375.03 | ||
| 1357.05 | ||
| 1473.13 | ||
| 1501.23 | ||
| 1316.99 | ||
| 1515.21 | ||
| 1259.94 | ||
| 1419.08 | ||
| 1300.99 | ||
| 1273.96 | ||
| 1429.08 | ||
| 1350.02 | ||
| 1471.16 | ||
| 1302.02 | ||
| 1343.03 | ||
| 1463.13 | ||
| 1457.18 | ||
| 1420.14 |