Assay Report Card

Basic Information

ID: ALA4685776

Type: Binding

Description: Protac activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation at 3.7 to 300 nM measured after 16 hrs in presence of proteasome inhibitor MG-132 by immunoblotting analysis

Organism: Homo sapiens

Cell type: MOLT-4

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1350.02