Assay Report Card

Basic Information

ID: ALA4685839

Type: ADME

Description: Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit at 50 uM using Z-nLPnLD-Glo as substrate incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
576.722.322.32
563.653.663.66
533.634.044.04
645.784.324.32
639.754.784.78
529.633.643.64
611.703.563.56
529.633.263.26
606.741.941.94
644.175.915.91
654.724.684.68
620.772.332.33
590.742.712.71
688.625.535.53
623.755.085.08
590.742.712.71
626.155.225.22
499.613.633.63
620.772.332.33
641.723.673.67
559.663.273.27
640.185.525.52
627.703.273.27
533.633.173.17
675.804.334.33