Basic Information
ID: ALA4685840
Type: ADME
Description: Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Z-LRR-Glo as substrate at 50 uM incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4685840
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 576.72 | 2.32 | 2.32 |
| 563.65 | 3.66 | 3.66 |
| 533.63 | 4.04 | 4.04 |
| 645.78 | 4.32 | 4.32 |
| 639.75 | 4.78 | 4.78 |
| 529.63 | 3.64 | 3.64 |
| 611.70 | 3.56 | 3.56 |
| 529.63 | 3.26 | 3.26 |
| 606.74 | 1.94 | 1.94 |
| 644.17 | 5.91 | 5.91 |
| 654.72 | 4.68 | 4.68 |
| 620.77 | 2.33 | 2.33 |
| 590.74 | 2.71 | 2.71 |
| 688.62 | 5.53 | 5.53 |
| 623.75 | 5.08 | 5.08 |
| 590.74 | 2.71 | 2.71 |
| 626.15 | 5.22 | 5.22 |
| 499.61 | 3.63 | 3.63 |
| 620.77 | 2.33 | 2.33 |
| 641.72 | 3.67 | 3.67 |
| 559.66 | 3.27 | 3.27 |
| 640.18 | 5.52 | 5.52 |
| 627.70 | 3.27 | 3.27 |
| 533.63 | 3.17 | 3.17 |
| 675.80 | 4.33 | 4.33 |