Basic Information
ID: ALA4685845
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus expression system using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4685845
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 357.41 | 4.57 | 4.57 |
| 394.82 | 4.31 | 4.31 |
| 413.36 | 5.15 | 5.15 |
| 279.30 | 3.10 | 3.10 |
| 419.44 | 4.28 | 4.28 |
| 329.36 | 4.25 | 4.25 |
| 347.35 | 4.39 | 4.39 |
| 343.39 | 4.18 | 4.18 |
| 435.48 | 5.83 | 5.83 |
| 329.36 | 4.25 | 4.25 |
| 408.26 | 5.01 | 5.01 |
| 333.39 | 3.98 | 3.98 |