Basic Information
ID: ALA4686126
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: VHL/EGFR(ALA4523998)
Document: ALA4680227
Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as EGFR degradation by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4686126
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1136.43 | ||
| 1066.34 | ||
| 1038.29 | ||
| 1052.27 | ||
| 1108.38 | ||
| 1094.40 | ||
| 1122.45 | ||
| 1080.33 | ||
| 1010.23 |