Basic Information
ID: ALA4686150
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 10 to 100 nM measured after 1 hr in presence of protein synthesis inhibitor cycloheximide by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: VHL/EGFR(ALA4523998)
Document: ALA4680227
Protac activity at VHL/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 10 to 100 nM measured after 1 hr in presence of protein synthesis inhibitor cycloheximide by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4686150
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1038.29 |