Basic Information
ID: ALA4686182
Type: Binding
Description: Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-1(ALA221)
Document: ALA4680229
Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4686182
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.12 | 1.09 | 1.09 |
| 280.33 | 2.85 | 2.85 |
| 296.33 | 2.55 | 2.55 |
| 314.77 | 3.50 | 3.50 |
| 294.35 | 3.15 | 3.15 |
| 294.35 | 3.15 | 3.15 |
| 385.47 | 4.89 | 4.89 |
| 296.33 | 2.55 | 2.55 |
| 417.94 | 6.15 | 6.15 |
| 323.40 | 2.91 | 2.91 |
| 330.39 | 4.00 | 4.00 |
| 369.47 | 4.91 | 4.91 |
| 369.47 | 5.19 | 5.19 |
| 403.91 | 5.85 | 5.85 |
| 433.94 | 5.85 | 5.85 |
| 355.44 | 4.88 | 4.88 |
| 389.89 | 5.54 | 5.54 |
| 294.35 | 3.15 | 3.15 |
| 383.50 | 5.50 | 5.50 |
| 293.37 | 3.18 | 3.18 |
| 371.44 | 4.59 | 4.59 |
| 298.32 | 2.99 | 2.99 |
| 307.40 | 3.21 | 3.21 |
| 399.49 | 5.21 | 5.21 |