Basic Information
ID: ALA4686909
Type: Binding
Description: Antagonist activity at NMDAR in embryonic cultures of rat cortical neuron assessed as inhibition of NMDA-induced calcium influx preincubated for 10 mins followed by NMDA addition by Fluo-4/AM dye based fluorescence assay
Format: BAO_0000221
Organism: Rattus norvegicus
Cell type: Cortical neuron
Target: Glutamate NMDA receptor(ALA1907608)
Document: ALA4680250
Antagonist activity at NMDAR in embryonic cultures of rat cortical neuron assessed as inhibition of NMDA-induced calcium influx preincubated for 10 mins followed by NMDA addition by Fluo-4/AM dye based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4686909
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.31 | 2.69 | 2.69 |
| 309.34 | 3.30 | 3.30 |
| 339.82 | 4.06 | 4.06 |
| 305.38 | 3.47 | 3.47 |
| 339.82 | 4.06 | 4.06 |
| 309.34 | 3.30 | 3.30 |
| 339.82 | 4.06 | 4.06 |
| 325.80 | 3.81 | 3.81 |
| 325.80 | 3.81 | 3.81 |
| 370.25 | 3.92 | 3.92 |
| 370.25 | 3.92 | 3.92 |
| 339.82 | 4.12 | 4.12 |