Basic Information
ID: ALA4687433
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged full length USP7 expressed in baculovirus infected Sf21 cells using monoubiquitinated ubiquitin-rhodamine as substrate incubated for 30 mins followed by Ub-Rho addition and measured after 2 hrs by spectrophotometry
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4687433
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.47 | 3.03 | 3.03 |
| 540.00 | 3.58 | 3.58 |
| 492.94 | 3.27 | 3.27 |
| 546.83 | 4.16 | 4.16 |
| 485.92 | 3.54 | 3.54 |
| 491.52 | 2.54 | 2.54 |
| 512.38 | 3.51 | 3.51 |
| 491.52 | 2.54 | 2.54 |
| 525.97 | 3.19 | 3.19 |
| 628.65 | 2.80 | 2.80 |
| 637.14 | 4.29 | 4.29 |
| 579.06 | 2.90 | 2.90 |
| 434.48 | 2.14 | 2.14 |
| 451.48 | 2.89 | 2.89 |
| 526.96 | 2.52 | 2.52 |
| 570.42 | 3.30 | 3.30 |
| 524.98 | 2.76 | 2.76 |
| 525.97 | 3.12 | 3.12 |
| 433.49 | 2.75 | 2.75 |
| 779.09 | 2.72 | 2.72 |
| 502.38 | 4.06 | 4.06 |
| 478.48 | 2.66 | 2.66 |
| 501.48 | 3.77 | 3.77 |
| 434.48 | 2.14 | 2.14 |
| 447.51 | 3.06 | 3.06 |
| 535.93 | 4.42 | 4.42 |
| 467.93 | 3.40 | 3.40 |
| 478.48 | 2.66 | 2.66 |
| 512.38 | 3.51 | 3.51 |
| 502.38 | 4.06 | 4.06 |
| 458.50 | 2.62 | 2.62 |
| 458.50 | 2.62 | 2.62 |
| 510.78 | 2.36 | 2.36 |
| 509.51 | 2.67 | 2.67 |
| 447.51 | 3.06 | 3.06 |
| 434.48 | 2.14 | 2.14 |
| 491.52 | 2.54 | 2.54 |
| 467.93 | 3.40 | 3.40 |
| 537.39 | 3.38 | 3.38 |
| 510.96 | 2.50 | 2.50 |
| 467.93 | 3.40 | 3.40 |
| 478.48 | 2.66 | 2.66 |
| 451.48 | 2.89 | 2.89 |
| 509.59 | 4.34 | 4.34 |
| 511.94 | 3.10 | 3.10 |