Basic Information
ID: ALA4687611
Type: Binding
Description: Inhibition of human C-terminal 6His-tagged CD73 (1 to 547 residues) expressed in HEK293F cells using 2 uM AMP as substrate by rapidfire mass spectrometry assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293F
Target: 5'-nucleotidase(ALA5957)
Document: ALA4680277
Inhibition of human C-terminal 6His-tagged CD73 (1 to 547 residues) expressed in HEK293F cells using 2 uM AMP as substrate by rapidfire mass spectrometry assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4687611
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.29 | 1.43 | 1.43 |
| 274.28 | 0.80 | 0.80 |
| 283.29 | 0.91 | 0.91 |
| 308.29 | 1.59 | 1.59 |
| 260.25 | 0.41 | 0.41 |
| 302.33 | 1.58 | 1.58 |
| 302.33 | 1.43 | 1.43 |
| 314.68 | 1.69 | 1.69 |
| 290.30 | 1.29 | 1.29 |
| 255.24 | 0.27 | 0.27 |
| 328.71 | 1.93 | 1.93 |
| 306.75 | 2.08 | 2.08 |
| 306.75 | 1.93 | 1.93 |
| 300.65 | 1.30 | 1.30 |
| 314.68 | 1.54 | 1.54 |
| 291.22 | 0.51 | 0.51 |
| 269.26 | 0.66 | 0.66 |
| 315.16 | 1.44 | 1.44 |
| 300.36 | 1.98 | 1.98 |
| 264.67 | 1.05 | 1.05 |
| 272.31 | 1.34 | 1.34 |
| 283.29 | 1.05 | 1.05 |
| 280.23 | 0.89 | 0.89 |
| 305.24 | 0.76 | 0.76 |
| 310.26 | 1.04 | 1.04 |
| 286.33 | 1.59 | 1.59 |
| 292.73 | 1.83 | 1.83 |
| 297.32 | 1.15 | 1.15 |
| 294.26 | 1.20 | 1.20 |