Assay Report Card

Basic Information

ID: ALA4687737

Type: ADME

Description: Mixed type inhibition of CYP17 in Sprague-Dawley rat testis microsomes assessed as reduction in 17alpha-Hydroxylase activity in presence of NADPH-generating system incubated for 2 mins by Lineweaver-Burk plot analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Testis

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
314.475.855.85