Basic Information
ID: ALA4687995
Type: Binding
Description: Inhibition of N,N'-Ethylenebis(iodoacetamide) binding to beta-tubulin colchicine binding site in human K562 cells assessed as reduction in EBI/beta-tubulin adduct formation at 1 to 10 uM preincubated for 2.5 hrs followed by EBI addition and measured after 1.5 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4687995
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.50 | 3.96 | 3.96 |
| 413.48 | 3.95 | 3.95 |