Inhibition of N-terminal His tagged human Pin1 expressed in Escherichia coli BL21 (DE3) using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate preincub...

Basic Information

ID: ALA4688201

Type: Binding

Description: Inhibition of N-terminal His tagged human Pin1 expressed in Escherichia coli BL21 (DE3) using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate preincubated with enzyme for 10 mins followed by substrate addition by UV-Vis spectrophotometer analysis

Format: BAO_0000019

Organism: Homo sapiens

Target: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(ALA2288)

Document: ALA4680296

Inhibition of N-terminal His tagged human Pin1 expressed in Escherichia coli BL21 (DE3) using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate preincubated with enzyme for 10 mins followed by substrate addition by UV-Vis spectrophotometer analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4688201

IC50

Total(51)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
363.39	4.27	4.27
416.50	2.85	2.85
410.50	4.04	4.04
440.53	3.66	3.66
438.55	4.67	4.67
426.50	2.86	2.86
422.51	4.04	4.04
424.48	3.21	3.21
440.53	3.40	3.40
439.54	3.23	3.23
424.48	2.88	2.88
440.53	3.25	3.25
440.53	3.66	3.66
408.48	3.81	3.81
412.47	2.62	2.62
424.53	4.28	4.28
440.53	3.66	3.66
443.31	3.04	3.04
440.53	3.66	3.66
428.54	3.60	3.60
426.50	3.27	3.27
454.51	3.00	3.00
425.51	2.84	2.84
468.54	3.39	3.39
396.47	3.65	3.65
426.50	3.27	3.27
435.51	3.79	3.79
440.53	3.66	3.66
426.50	3.01	3.01
468.54	3.39	3.39
478.50	4.82	4.82
426.50	3.27	3.27
439.54	2.80	2.80
425.51	2.80	2.80
426.50	3.01	3.01
424.53	4.28	4.28
412.47	2.62	2.62
425.47	1.98	1.98
440.53	3.66	3.66
414.46	3.59	3.59
439.54	3.19	3.19
424.53	4.43	4.43
411.49	2.45	2.45
421.53	3.84	3.84
439.54	3.23	3.23
450.52	3.40	3.40
412.47	2.88	2.88
423.49	3.40	3.40
452.54	3.54	3.54
438.55	4.82	4.82