ID: ALA4688263
Type: Binding
Description: Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by quanti-blue based SEAP assay
Organism: Homo sapiens
Cell type: HEK-Blue CD40L
Bioactivity
Activity Types for Assay ALA4688263
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
437.91 | 5.28 | 5.28 |
437.91 | 5.28 | 5.28 |
436.92 | 5.88 | 5.88 |
423.52 | 4.58 | 4.58 |
471.36 | 6.54 | 6.54 |
419.92 | 5.14 | 5.14 |
350.43 | 5.53 | 5.53 |
454.91 | 6.02 | 6.02 |
471.58 | 5.83 | 5.83 |
454.91 | 6.02 | 6.02 |
464.97 | 6.52 | 6.52 |
404.90 | 5.18 | 5.18 |
521.00 | 4.86 | 4.86 |
471.36 | 6.54 | 6.54 |
461.93 | 5.76 | 5.76 |
436.92 | 5.88 | 5.88 |
418.93 | 5.75 | 5.75 |
436.92 | 5.88 | 5.88 |
432.96 | 6.24 | 6.24 |
434.94 | 7.09 | 7.09 |
471.36 | 6.54 | 6.54 |
384.87 | 6.18 | 6.18 |
432.95 | 5.92 | 5.92 |
494.93 | 5.60 | 5.60 |
418.93 | 5.93 | 5.93 |
398.51 | 5.59 | 5.59 |
418.93 | 5.75 | 5.75 |
451.93 | 5.47 | 5.47 |
512.01 | 4.89 | 4.89 |
436.92 | 5.88 | 5.88 |
455.94 | 5.67 | 5.67 |
437.91 | 5.28 | 5.28 |
361.67 | 6.01 | 6.01 |
450.95 | 6.27 | 6.27 |
506.03 | 6.49 | 6.49 |
486.93 | 6.76 | 6.76 |
422.89 | 6.06 | 6.06 |