Assay Report Card

Basic Information

ID: ALA4688314

Type: Unassigned

Description: Selectivity ratio of drug exposure in TNFalpha-induced C57BL/6J mouse at 5 mg/kg, po at 3 hrs post dose to IC50 for inhibition of human TNFalpha expressed in HEK-Blue-CD40L cells assessed as inhibition of NFkappaB activation by quanti-blue based SEAP assay

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
494.935.605.60