ID: ALA4688315
Type: Unassigned
Description: Selectivity ratio of drug exposure in TNFalpha-induced C57BL/6J mouse at 25 mg/kg, po at 3 hrs post dose to IC50 for inhibition of human TNFalpha expressed in HEK-Blue-CD40L cells assessed as inhibition of NFkappaB activation by quanti-blue based SEAP assay
Bioactivity
Activity Types for Assay ALA4688315
Selectivity ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
494.93 | 5.60 | 5.60 |