Basic Information
ID: ALA4688332
Type: Unassigned
Description: Selectivity ratio of drug exposure in anticollagen antibody-induced arthritis BALB/c mouse model at 2 mg/kg, po BID for 12 days to IC50 for inhibition of human TNFalpha expressed in HEK-Blue-CD40L cells assessed as inhibition of NFkappaB activation by quanti-blue based SEAP assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4688332
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.93 | 5.60 | 5.60 |