Basic Information
ID: ALA4688353
Type: Functional
Description: Antiviral activity against lamivudine/entecavir-resistant HBV rtL180M/rtM204V/rtT184L mutant infected in human HepG2 2.2.15 cells assessed as inhibition of viral DNA replication at 0.8 uM measured after incubation of 72 hrs by RT-PCR analysis relative to control
Format: BAO_0000218
Organism: Hepatitis B virus
Cell type: HepG2 2.2.15
Target: Hepatitis B virus(ALA613497)
Document: ALA4680304
Antiviral activity against lamivudine/entecavir-resistant HBV rtL180M/rtM204V/rtT184L mutant infected in human HepG2 2.2.15 cells assessed as inhibition of viral DNA replication at 0.8 uM measured after incubation of 72 hrs by RT-PCR analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4688353
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 548.26 | 5.21 | 5.21 |
| 497.36 | 4.04 | 4.04 |