Basic Information
ID: ALA4688479
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as dansyl glutathione adduct formation at 100 microM incubated for 30 mins by HPLC/MS based fluorescence analysis relative to diclofenac dGSH adduct
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4680310
Drug metabolism in human liver microsomes assessed as dansyl glutathione adduct formation at 100 microM incubated for 30 mins by HPLC/MS based fluorescence analysis relative to diclofenac dGSH adduct: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4688479
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.42 | 4.39 | 4.39 |
| 384.48 | 4.43 | 4.43 |
| 370.45 | 4.04 | 4.04 |
| 422.89 | 4.84 | 4.84 |
| 388.44 | 4.18 | 4.18 |
| 437.90 | 4.54 | 4.54 |
| 412.41 | 4.53 | 4.53 |
| 407.42 | 3.72 | 3.72 |
| 371.44 | 3.44 | 3.44 |
| 404.90 | 4.70 | 4.70 |
| 388.44 | 4.18 | 4.18 |
| 423.88 | 4.23 | 4.23 |
| 406.43 | 4.32 | 4.32 |
| 372.42 | 3.49 | 3.49 |
| 412.41 | 4.53 | 4.53 |
| 408.45 | 4.70 | 4.70 |
| 409.44 | 3.98 | 3.98 |
| 453.90 | 4.24 | 4.24 |
| 404.90 | 4.70 | 4.70 |
| 358.44 | 4.12 | 4.12 |
| 410.42 | 4.10 | 4.10 |
| 438.89 | 3.81 | 3.81 |