In vivo antagonist activity at TRPM8 in po dosed Sprague-Dawley rat assessed as inhibition of icilin-induced wet dog shakes administered 1 to 4 hrs pr...

Basic Information

ID: ALA4688510

Type: Functional

Description: In vivo antagonist activity at TRPM8 in po dosed Sprague-Dawley rat assessed as inhibition of icilin-induced wet dog shakes administered 1 to 4 hrs prior to icilin administration and measured after 5 mins for 5 mins relative to KPR-2579

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Unchecked(ALA612545)

Document:  ALA4680310

In vivo antagonist activity at TRPM8 in po dosed Sprague-Dawley rat assessed as inhibition of icilin-induced wet dog shakes administered 1 to 4 hrs prior to icilin administration and measured after 5 mins for 5 mins relative to KPR-2579: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
437.904.544.54