Basic Information
ID: ALA4689035
Type: Binding
Description: Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production at 0.3 uM using sphingosine as substrate in presence of [gamma33P]-ATP by scintillation counting method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4689035
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.99 | 4.78 | 4.78 |
| 463.93 | 6.12 | 6.12 |
| 369.94 | 4.00 | 4.00 |
| 424.07 | 6.29 | 6.29 |
| 353.98 | 4.94 | 4.94 |
| 463.93 | 6.12 | 6.12 |
| 384.00 | 5.16 | 5.16 |
| 410.09 | 6.42 | 6.42 |
| 375.94 | 4.73 | 4.73 |
| 395.93 | 5.10 | 5.10 |
| 375.94 | 4.73 | 4.73 |
| 382.03 | 5.72 | 5.72 |
| 401.86 | 4.24 | 4.24 |
| 463.93 | 6.12 | 6.12 |
| 373.97 | 4.38 | 4.38 |
| 341.92 | 3.99 | 3.99 |
| 396.06 | 6.11 | 6.11 |
| 463.93 | 6.12 | 6.12 |
| 402.02 | 5.16 | 5.16 |
| 400.01 | 5.42 | 5.42 |
| 397.87 | 4.83 | 4.83 |
| 388.00 | 4.77 | 4.77 |
| 345.91 | 3.74 | 3.74 |
| 368.01 | 5.33 | 5.33 |
| 355.95 | 4.38 | 4.38 |
| 319.83 | 3.44 | 3.44 |
| 395.93 | 5.10 | 5.10 |
| 369.98 | 4.77 | 4.77 |
| 383.96 | 4.39 | 4.39 |
| 361.91 | 3.44 | 3.44 |