Assay Report Card

Basic Information

ID: ALA4689083

Type: Binding

Description: Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced YO-PRO-1 uptake by cells at 10 uM incubated for 1 hr by fluorescence based assay relative to control

Organism: Mus musculus

Cell type: N2a

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
832.069.319.31
350.35-0.15-0.15
410.40-0.12-0.12
610.591.771.77
382.39-0.54-0.54