Basic Information
ID: ALA4689468
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells using Biotin-H4K2Ome2 as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4689468
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.38 | 3.85 | 3.85 |
| 264.28 | 3.48 | 3.48 |
| 361.45 | 4.78 | 4.78 |
| 266.30 | 3.72 | 3.72 |
| 349.43 | 4.63 | 4.63 |
| 368.44 | 4.50 | 4.50 |
| 363.46 | 4.66 | 4.66 |
| 399.49 | 5.79 | 5.79 |
| 360.46 | 4.44 | 4.44 |