Basic Information
ID: ALA4689516
Type: Binding
Description: Protac activity at CRBN/JAK2 V617 mutant in human HEL cells assessed as decrease in JAK2 V617 mutant protein level at < 60 nM measured after 24 hrs by immunoblotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEL
Target: Unchecked(ALA612545)
Document: ALA4680361
Protac activity at CRBN/JAK2 V617 mutant in human HEL cells assessed as decrease in JAK2 V617 mutant protein level at < 60 nM measured after 24 hrs by immunoblotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4689516
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 889.05 | 4.64 | 4.64 |