Basic Information
ID: ALA4689606
Type: Unassigned
Description: Selectivity index, ratio of IC50 for Class 1/2b HDAC in human Jurkat E6.1 cells using Boc-Lys-(Ac)-AMC as substrate to IC50 for Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4680373
Selectivity index, ratio of IC50 for Class 1/2b HDAC in human Jurkat E6.1 cells using Boc-Lys-(Ac)-AMC as substrate to IC50 for Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4689606
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.36 | 2.97 | 2.97 |
| 382.39 | 3.36 | 3.36 |
| 398.43 | 4.00 | 4.00 |
| 368.36 | 2.97 | 2.97 |
| 380.37 | 3.11 | 3.11 |
| 396.41 | 3.75 | 3.75 |
| 354.33 | 2.58 | 2.58 |
| 418.37 | 3.60 | 3.60 |
| 404.34 | 3.21 | 3.21 |
| 382.39 | 3.36 | 3.36 |
| 448.39 | 3.58 | 3.58 |
| 448.39 | 3.58 | 3.58 |
| 410.44 | 4.00 | 4.00 |
| 382.39 | 3.36 | 3.36 |
| 400.38 | 3.31 | 3.31 |
| 382.39 | 3.36 | 3.36 |