Assay Report Card

Basic Information

ID: ALA4689677

Type: ADME

Description: In vivo inhibition of Class 1 HDAC in CBAxC57BL/6J mouse brain assessed as increase in histone H4 acetylation at 30 to 100 mg/kg, po bid for 14.5 days by western blot analysis

Organism: Mus musculus

Strain: CBAxC57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
382.393.363.36