Basic Information
ID: ALA4689780
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as intrinsic clearance half life
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4680377
Metabolic stability in rat liver microsomes assessed as intrinsic clearance half life: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4689780
t1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.39 | 3.31 | 3.31 |
| 408.43 | 4.10 | 4.10 |
| 405.43 | 3.88 | 3.88 |
| 434.50 | 3.93 | 3.93 |
| 421.47 | 4.01 | 4.01 |
| 419.46 | 4.14 | 4.14 |
| 420.44 | 4.53 | 4.53 |
| 444.53 | 5.53 | 5.53 |
| 434.50 | 3.93 | 3.93 |
| 404.40 | 3.98 | 3.98 |
| 408.43 | 4.10 | 4.10 |
| 410.47 | 4.43 | 4.43 |
| 436.51 | 4.35 | 4.35 |
| 390.37 | 3.52 | 3.52 |
| 407.45 | 3.62 | 3.62 |
| 446.48 | 5.15 | 5.15 |
| 454.46 | 4.81 | 4.81 |
| 437.50 | 3.47 | 3.47 |
| 420.44 | 4.61 | 4.61 |
| 438.43 | 4.68 | 4.68 |
| 438.46 | 3.76 | 3.76 |
| 394.40 | 3.71 | 3.71 |
| 424.50 | 4.82 | 4.82 |
| 406.41 | 4.22 | 4.22 |
| 408.45 | 4.68 | 4.68 |
| 440.86 | 4.88 | 4.88 |
| 434.47 | 5.00 | 5.00 |
| 420.44 | 4.54 | 4.54 |
| 394.40 | 3.71 | 3.71 |
| 438.46 | 3.76 | 3.76 |
| 438.43 | 4.68 | 4.68 |
| 470.45 | 5.42 | 5.42 |
| 406.41 | 4.22 | 4.22 |
| 430.50 | 4.97 | 4.97 |
| 392.39 | 3.97 | 3.97 |
| 392.39 | 3.97 | 3.97 |
| 438.46 | 3.76 | 3.76 |
| 406.41 | 4.22 | 4.22 |
| 440.43 | 4.62 | 4.62 |
| 422.48 | 4.94 | 4.94 |
| 438.46 | 3.76 | 3.76 |
| 405.43 | 3.80 | 3.80 |
| 392.39 | 3.76 | 3.76 |
| 432.45 | 4.76 | 4.76 |
| 418.42 | 4.30 | 4.30 |
| 424.50 | 4.82 | 4.82 |
| 407.45 | 3.67 | 3.67 |
| 393.42 | 3.28 | 3.28 |