Basic Information
ID: ALA4689794
Type: Functional
Description: In vivo antagonist activity at EP3 in iv dosed Sprague-Dawley rat assessed as reversal of sulprostone-induced suppression of glucose-stimulated insulin secretion by measuring circulating insulin levels at 7 times Ki measured up to 30 mins by intravenous glucose tolerance test
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Unchecked(ALA612545)
Document: ALA4680377
In vivo antagonist activity at EP3 in iv dosed Sprague-Dawley rat assessed as reversal of sulprostone-induced suppression of glucose-stimulated insulin secretion by measuring circulating insulin levels at 7 times Ki measured up to 30 mins by intravenous glucose tolerance test: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4689794
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.41 | 4.22 | 4.22 |