ID: ALA4699851
Type: Functional
Description: Antagonist activity at Y1 receptor in human HEL cells assessed as reduction in pNPY-induced calcium mobilization preincubated for 15 mins followed by pNPY stimulation and measured immediately by Fura-2 dye based fluorescence assay
Organism: Homo sapiens
Cell type: HEL
Bioactivity
Activity Types for Assay ALA4699851
pKb
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
751.71 | 2.10 | 2.10 |
715.73 | 1.86 | 1.86 |
741.77 | 2.25 | 2.25 |
733.72 | 1.81 | 1.81 |
867.93 | 4.67 | 4.67 |
797.88 | 3.81 | 3.81 |
769.70 | 2.40 | 2.40 |
783.85 | 3.42 | 3.42 |
743.78 | 2.64 | 2.64 |
730.74 | 0.79 | 0.79 |
727.74 | 2.02 | 2.02 |
769.82 | 3.03 | 3.03 |
743.78 | 2.49 | 2.49 |
757.81 | 2.88 | 2.88 |
755.79 | 2.64 | 2.64 |
729.76 | 2.25 | 2.25 |
1049.08 | 6.12 | 6.12 |
795.79 | 3.29 | 3.29 |
791.83 | 3.08 | 3.08 |
794.63 | 2.23 | 2.23 |
808.65 | 2.62 | 2.62 |
777.80 | 3.15 | 3.15 |
750.17 | 2.07 | 2.07 |
764.20 | 2.46 | 2.46 |
731.73 | 0.83 | 0.83 |