Basic Information
ID: ALA4700126
Type: Binding
Description: Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphorylation using peptide 11 as substrate measured after 30 mins in presence of 30 uM ATP by caliper EZ reader analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase NEK2(ALA3835)
Document: ALA4699418
Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphorylation using peptide 11 as substrate measured after 30 mins in presence of 30 uM ATP by caliper EZ reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4700126
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.33 | 0.73 | 0.73 |
| 318.36 | 1.31 | 1.31 |
| 235.25 | 2.08 | 2.08 |
| 366.43 | 3.15 | 3.15 |
| 292.30 | 2.04 | 2.04 |
| 306.33 | 1.37 | 1.37 |
| 306.33 | 1.50 | 1.50 |
| 306.33 | 1.78 | 1.78 |
| 320.36 | 1.84 | 1.84 |
| 278.28 | 1.18 | 1.18 |
| 290.29 | 1.57 | 1.57 |
| 328.36 | 0.87 | 0.87 |
| 236.24 | 1.97 | 1.97 |
| 292.30 | 1.44 | 1.44 |
| 278.28 | 1.18 | 1.18 |
| 320.36 | 1.71 | 1.71 |
| 356.41 | 1.47 | 1.47 |
| 318.34 | 1.71 | 1.71 |
| 306.33 | 1.78 | 1.78 |
| 292.30 | 1.11 | 1.11 |
| 291.31 | 2.21 | 2.21 |
| 318.34 | 1.59 | 1.59 |
| 327.37 | 1.62 | 1.62 |
| 306.33 | 1.37 | 1.37 |
| 290.29 | 1.57 | 1.57 |
| 292.30 | 1.11 | 1.11 |
| 363.38 | 0.65 | 0.65 |
| 292.30 | 1.44 | 1.44 |
| 320.36 | 1.71 | 1.71 |