Basic Information
ID: ALA4700242
Type: Binding
Description: Metal chelating activity assessed as inhibition of human DMT1 expressed in HEK293T cells by measuring inhibition of radiolabeled 55Fe2+ uptake preincubated with compound for 5 mins followed by incubation with Fe2+ and radiolabeled 55Fe2+ for 15 mins at extracellular pH of 5.5 by scintillation counting analysis
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4700242
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 204.23 | 1.29 | 1.29 |
| 362.31 | 3.55 | 3.55 |
| 218.26 | 1.60 | 1.60 |
| 244.30 | 1.45 | 1.45 |
| 232.29 | 1.44 | 1.44 |
| 218.26 | 1.19 | 1.19 |
| 232.29 | 1.39 | 1.39 |
| 258.32 | 1.71 | 1.71 |
| 270.34 | 2.02 | 2.02 |