Basic Information
ID: ALA4700243
Type: Binding
Description: Metal chelating activity assessed as inhibition of human DMT1 expressed in HEK293T cells by measuring inhibition of radiolabeled 55Fe2+ uptake at 10 uM preincubated with compound for 5 mins followed by incubation with Fe2+ and radiolabeled 55Fe2+ for 15 mins at extracellular pH of 5.5 by scintillation counting analysis
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4700243
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 204.23 | 1.29 | 1.29 |
| 362.31 | 3.55 | 3.55 |
| 202.26 | 1.90 | 1.90 |
| 264.24 | -0.27 | -0.27 |
| 246.31 | 1.87 | 1.87 |
| 220.23 | 0.12 | 0.12 |
| 246.27 | 0.65 | 0.65 |
| 294.36 | 2.47 | 2.47 |
| 244.30 | 1.45 | 1.45 |
| 245.29 | 0.22 | 0.22 |
| 296.33 | 1.46 | 1.46 |
| 230.27 | 1.06 | 1.06 |
| 220.23 | 0.12 | 0.12 |
| 280.33 | 2.55 | 2.55 |
| 393.33 | 2.14 | 2.14 |
| 266.30 | 2.24 | 2.24 |