Assay Report Card

Basic Information

ID: ALA4700253

Type: Binding

Description: Metal chelating activity assessed as inhibition of human ZIP8 expressed in HEK293T cells by measuring inhibition of radiolabeled 55Fe2+ uptake at 10 uM preincubated with compound for 5 mins followed by incubation with Fe2+ and radiolabeled 55Fe2+ for 15 mins at extracellular pH of 7.4 by scintillation counting analysis

Cell type: HEK293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
204.231.291.29
362.313.553.55
344.473.843.84
244.301.451.45