Basic Information
ID: ALA4700533
Type: Functional
Description: Inhibition of LPS-induced TNFalpha production in human THP-1 cells incubated for 2 hrs followed by LPS stimulation and measured after 12 hrs by ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4700533
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.47 | 6.11 | 6.11 |
| 383.62 | 7.68 | 7.68 |
| 417.63 | 6.79 | 6.79 |
| 371.61 | 7.34 | 7.34 |
| 177.25 | 2.10 | 2.10 |
| 345.57 | 6.78 | 6.78 |
| 373.62 | 7.56 | 7.56 |
| 369.59 | 7.12 | 7.12 |
| 412.66 | 8.72 | 8.72 |
| 441.74 | 8.52 | 8.52 |
| 397.65 | 7.99 | 7.99 |
| 397.69 | 8.77 | 8.77 |
| 369.64 | 8.15 | 8.15 |
| 397.65 | 7.85 | 7.85 |
| 386.65 | 8.26 | 8.26 |
| 401.61 | 7.82 | 7.82 |
| 370.58 | 6.94 | 6.94 |
| 383.62 | 7.16 | 7.16 |
| 389.62 | 6.41 | 6.41 |
| 411.67 | 8.24 | 8.24 |
| 451.62 | 8.70 | 8.70 |
| 411.67 | 8.29 | 8.29 |
| 355.57 | 7.44 | 7.44 |
| 413.65 | 7.69 | 7.69 |
| 383.62 | 7.46 | 7.46 |
| 399.62 | 6.65 | 6.65 |
| 389.67 | 7.88 | 7.88 |
| 399.62 | 7.38 | 7.38 |
| 397.65 | 7.55 | 7.55 |
| 427.74 | 9.09 | 9.09 |
| 233.35 | 3.66 | 3.66 |
| 399.69 | 8.48 | 8.48 |
| 502.94 | 5.59 | 5.59 |
| 397.65 | 7.99 | 7.99 |
| 397.65 | 7.99 | 7.99 |
| 462.52 | 8.44 | 8.44 |
| 370.58 | 7.54 | 7.54 |
| 363.63 | 7.35 | 7.35 |
| 397.65 | 8.07 | 8.07 |