Basic Information
ID: ALA4701026
Type: Functional
Description: Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins followed by 3 nM A2A agonist NECA addition and measured after 30 mins by EU-cAMP tracer based TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Adenosine A2a receptor(ALA251)
Document: ALA4699449
Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins followed by 3 nM A2A agonist NECA addition and measured after 30 mins by EU-cAMP tracer based TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701026
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.57 | 1.47 | 1.47 |
| 604.67 | 2.20 | 2.20 |