Basic Information
ID: ALA4701028
Type: Functional
Description: Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins followed by adenosine addition and measured after 30 mins by EU-cAMP tracer based TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Adenosine A2a receptor(ALA251)
Document: ALA4699449
Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins followed by adenosine addition and measured after 30 mins by EU-cAMP tracer based TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701028
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.57 | 1.47 | 1.47 |
| 604.67 | 2.20 | 2.20 |